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1.
Journal of Knowledge Management ; 27(5):1251-1278, 2023.
Artigo em Inglês | ProQuest Central | ID: covidwho-2312923

RESUMO

PurposeThe main purpose of this paper is to examine the direct effects of knowledge sharing and systems thinking on creativity and organizational sustainability in the hotel industry in Malaysia. In addition, the study aims to examine the mediation effect of creativity between knowledge sharing, systems thinking and organizational sustainability.Design/methodology/approachA survey method based on a questionnaire was used to gather data from 407 middle managers in the hotel industry in Malaysia. The partial least squares technique was used to examine the hypotheses.FindingsThe study found support for the effects of systems thinking and knowledge sharing on organizational sustainability. It also found support for the impact of creativity on organizational sustainability. Besides, the mediating role of creativity between systems thinking and organizational sustainability, and between knowledge sharing and organizational sustainability was also supported by data.Originality/valueThis is a pioneer work that has combined various human resources (i.e. systems thinking, knowledge sharing, creativity) to examine their impacts on organizational sustainability. Moreover, this work has established comparatively new relationships, i.e. the impact of systems thinking and knowledge sharing on creativity and organizational sustainability. In addition, the mediation role of creativity between systems thinking, knowledge sharing and organizational sustainability is relatively new in the literature. Furthermore, this study has confirmed the validity and reliability of knowledge sharing and organizational sustainability at first and second orders in the hotel industry in non-Western context.

2.
Genomics Proteomics Bioinformatics ; 19(5): 727-740, 2021 10.
Artigo em Inglês | MEDLINE | ID: covidwho-1474586

RESUMO

COVID-19 has swept globally and Pakistan is no exception. To investigate the initial introductions and transmissions of the SARS-CoV-2 in Pakistan, we performed the largest genomic epidemiology study of COVID-19 in Pakistan and generated 150 complete SARS-CoV-2 genome sequences from samples collected from March 16 to June 1, 2020. We identified a total of 347 mutated positions, 31 of which were over-represented in Pakistan. Meanwhile, we found over 1000 intra-host single-nucleotide variants (iSNVs). Several of them occurred concurrently, indicating possible interactions among them or coevolution. Some of the high-frequency iSNVs in Pakistan were not observed in the global population, suggesting strong purifying selections. The genomic epidemiology revealed five distinctive spreading clusters. The largest cluster consisted of 74 viruses which were derived from different geographic locations of Pakistan and formed a deep hierarchical structure, indicating an extensive and persistent nation-wide transmission of the virus that was probably attributed to a signature mutation (G8371T in ORF1ab) of this cluster. Furthermore, 28 putative international introductions were identified, several of which are consistent with the epidemiological investigations. In all, this study has inferred the possible pathways of introductions and transmissions of SARS-CoV-2 in Pakistan, which could aid ongoing and future viral surveillance and COVID-19 control.


Assuntos
COVID-19 , SARS-CoV-2 , COVID-19/epidemiologia , Genoma Viral , Genômica , Humanos , Paquistão/epidemiologia , Filogenia , SARS-CoV-2/genética
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